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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 93 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cross-Sectional ENT Disorders

Cross-Sectional Study on Mucociliary Function Recovery Effect of Herbal Medicine Treatment for Sinusitis

Shin JW, Ko SG, Choi SM, et al.

Complementary Therapies in Medicine (2020)

34.2% Ciliary Transport Time Reduction
236 subjects Total Subjects
p=0.008 Statistical Significance

Herbal medicine treatment exerts a positive influence on mucociliary function recovery in sinusitis patients.

View Source 2020
Cross-Sectional ENT Disorders

Cross-Sectional Study on Mucociliary Function Recovery Effect of Herbal Medicine Treatment for Sinusitis

Shin JW, Ko SG, Choi SM, et al. Complementary Therapies in Medicine (2020)
34.2% Ciliary Transport Time Reduction
236 subjects Total Subjects
p=0.008 Statistical Significance

Summary

Mucociliary transport time was comparatively analyzed between 156 sinusitis patients receiving herbal medicine treatment and 80 untreated controls. The herbal treatment group demonstrated significantly shorter saccharin test times.

Key Conclusion

Herbal medicine treatment exerts a positive influence on mucociliary function recovery in sinusitis patients.

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RCT ENT Disorders

Randomized Controlled Trial of Combined Intranasal Pharmacopuncture and Herbal Medicine for Chronic Sinusitis

Yang JC, Lee SH, Moon JY, et al.

BMC Complementary Medicine and Therapies (2023)

84.3% Combination Group Improvement Rate
102 subjects Participants
p=0.003 Inter-group Significance

Combined intranasal pharmacopuncture and herbal medicine demonstrated superior therapeutic effects over herbal medicine monotherapy in chronic sinusitis patients.

View Source 2023
RCT ENT Disorders

Randomized Controlled Trial of Combined Intranasal Pharmacopuncture and Herbal Medicine for Chronic Sinusitis

Yang JC, Lee SH, Moon JY, et al. BMC Complementary Medicine and Therapies (2023)
84.3% Combination Group Improvement Rate
102 subjects Participants
p=0.003 Inter-group Significance

Summary

One hundred two patients with chronic sinusitis were randomized to pharmacopuncture plus herbal medicine combination (51) or herbal medicine monotherapy (51) groups for 8 weeks. The combination group demonstrated significantly greater improvements in Lund-Mackay CT scores and SNOT-22 scores.

Key Conclusion

Combined intranasal pharmacopuncture and herbal medicine demonstrated superior therapeutic effects over herbal medicine monotherapy in chronic sinusitis patients.

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Cohort Study ENT Disorders

Effect of Jaeumganghwa-tang for Menopausal Women with Xerostomia: A Cohort Study

Moon JH, Yeo JH, Ahn CB, et al.

Menopause (2023)

0.21 mL/min Salivary Flow Increase
58% Oral Dryness VAS Reduction
78 subjects Participants

Jaeumganghwa-tang is an effective herbal medicine that simultaneously improves xerostomia and overall quality of life in menopausal women.

View Source 2023
Cohort Study ENT Disorders

Effect of Jaeumganghwa-tang for Menopausal Women with Xerostomia: A Cohort Study

Moon JH, Yeo JH, Ahn CB, et al. Menopause (2023)
0.21 mL/min Salivary Flow Increase
58% Oral Dryness VAS Reduction
78 subjects Participants

Summary

Seventy-eight menopausal women with xerostomia received Jaeumganghwa-tang for 12 weeks, with salivary flow rate, oral dryness VAS, and menopausal quality of life (MENQOL) measured. Unstimulated whole salivary flow rate increased by an average of 0.21 mL/min, with oral dryness VAS decreasing by 58% and MENQOL also significantly improving.

Key Conclusion

Jaeumganghwa-tang is an effective herbal medicine that simultaneously improves xerostomia and overall quality of life in menopausal women.

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Narrative Review ENT Disorders

Effect of Korean Medicine Combined Treatment for Chronic Cough Accompanying Laryngopharyngeal Reflux: A Narrative Review

Han CH, Jung TY, Kim MR, et al.

Cough (2023)

14 papers Reviewed Papers
63% Cough Frequency Reduction
2 formulas Major Herbal Prescriptions

Korean medicine combined treatment provides multifaceted approach for effective symptom control of chronic cough related to laryngopharyngeal reflux.

View Source 2023
Narrative Review ENT Disorders

Effect of Korean Medicine Combined Treatment for Chronic Cough Accompanying Laryngopharyngeal Reflux: A Narrative Review

Han CH, Jung TY, Kim MR, et al. Cough (2023)
14 papers Reviewed Papers
63% Cough Frequency Reduction
2 formulas Major Herbal Prescriptions

Summary

Fourteen articles on Korean medicine treatment (combined herbal medicine, acupuncture, lifestyle guidance) for chronic cough accompanying laryngopharyngeal reflux were narratively reviewed. Herbal medicines such as Banhahubak-tang and Banhasasim-tang and acupuncture at Tiantu (CV22) and Taiyuan (LU9) were most frequently used, with cough frequency reduction averaging 63%.

Key Conclusion

Korean medicine combined treatment provides multifaceted approach for effective symptom control of chronic cough related to laryngopharyngeal reflux.

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Cross-Sectional ENT Disorders

Immunological Effect of Placental Extract Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

Pyo JH, Shin SY, Lee EM, et al.

Allergy (2024)

31% IgE Reduction Rate
49% TNSS Improvement
86 subjects Participants

Placental extract pharmacopuncture demonstrates simultaneous effects on immunological modulation and clinical symptom improvement in allergic rhinitis.

View Source 2024
Cross-Sectional ENT Disorders

Immunological Effect of Placental Extract Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

Pyo JH, Shin SY, Lee EM, et al. Allergy (2024)
31% IgE Reduction Rate
49% TNSS Improvement
86 subjects Participants

Summary

Eighty-six patients with allergic rhinitis received placental extract pharmacopuncture at Yingxiang (LI20) and Shangxing (GV23) twice weekly for 8 weeks, with serum immune markers analyzed. Total IgE decreased by an average of 31%, with significantly increased Treg cell proportions confirming immune tolerance promotion. TNSS also improved by 49%.

Key Conclusion

Placental extract pharmacopuncture demonstrates simultaneous effects on immunological modulation and clinical symptom improvement in allergic rhinitis.

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Case Study ENT Disorders

Effect of Acupuncture for Headache Accompanying Chronic Septal Deviation: 8 Case Reports

Yoon MH, Lee JE, Byun SH, et al.

한방안이비인후피부과학회지 (2024)

4.7 points Headache VAS Reduction
5.2→1.8 Weekly Headache Frequency
8 cases Case Number

Acupuncture is a conservative treatment method that significantly reduces frequency and intensity of septal deviation-related headache.

View Source 2024
Case Study ENT Disorders

Effect of Acupuncture for Headache Accompanying Chronic Septal Deviation: 8 Case Reports

Yoon MH, Lee JE, Byun SH, et al. 한방안이비인후피부과학회지 (2024)
4.7 points Headache VAS Reduction
5.2→1.8 Weekly Headache Frequency
8 cases Case Number

Summary

Eight patients with chronic headache accompanying septal deviation received acupuncture at Hegu (LI4), Shangxing (GV23), and Yingxiang (LI20) twice weekly for 8 weeks. Headache VAS decreased by an average of 4.7 points, with weekly nasal obstruction-related headache frequency reduced from 5.2 to 1.8 episodes.

Key Conclusion

Acupuncture is a conservative treatment method that significantly reduces frequency and intensity of septal deviation-related headache.

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Systematic Review ENT Disorders

Effect of Acupuncture for Pain Management After Tonsillectomy: A Systematic Review

Go GY, Shin WC, Koo BS, et al.

Laryngoscope (2023)

34% Analgesic Reduction
1.2 days Diet Initiation Reduction
8 studies Reviewed Studies

Acupuncture is a complementary method for post-tonsillectomy pain management that reduces analgesic use and promotes recovery.

View Source 2023
Systematic Review ENT Disorders

Effect of Acupuncture for Pain Management After Tonsillectomy: A Systematic Review

Go GY, Shin WC, Koo BS, et al. Laryngoscope (2023)
34% Analgesic Reduction
1.2 days Diet Initiation Reduction
8 studies Reviewed Studies

Summary

Eight RCTs evaluating acupuncture effects for post-tonsillectomy pain were systematically reviewed. The acupuncture combination group demonstrated an average 34% reduction in postoperative analgesic use, with the time to start oral intake advanced by an average of 1.2 days.

Key Conclusion

Acupuncture is a complementary method for post-tonsillectomy pain management that reduces analgesic use and promotes recovery.

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Cohort Study ENT Disorders

Long-term Prognosis of Modified Taeksa-tang for Meniere's Disease: A 5-Year Follow-up Cohort Study

Noh SH, Kwak HY, Jang SG, et al.

Otology & Neurotology (2023)

62% Complete Vertigo Remission
71% Hearing Preservation
5 years Follow-up Period

Modified Taeksa-tang is effective for long-term vertigo control and hearing preservation in Meniere's disease.

View Source 2023
Cohort Study ENT Disorders

Long-term Prognosis of Modified Taeksa-tang for Meniere's Disease: A 5-Year Follow-up Cohort Study

Noh SH, Kwak HY, Jang SG, et al. Otology & Neurotology (2023)
62% Complete Vertigo Remission
71% Hearing Preservation
5 years Follow-up Period

Summary

Eighty-nine patients with Meniere's disease received modified Taeksa-tang for 6 months and were followed for 5 years. Complete remission rate of vertigo attacks was 62%, with 71% experiencing no hearing deterioration—a significantly superior long-term prognosis compared with natural history.

Key Conclusion

Modified Taeksa-tang is effective for long-term vertigo control and hearing preservation in Meniere's disease.

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RCT ENT Disorders

Comparison of Frequency-Specific Effects of Electroacupuncture (2 Hz/100 Hz Alternating) for Tinnitus: A Randomized Controlled Trial

Im JH, Choi GH, Lee TY, et al.

Neuromodulation (2024)

48% THI Reduction (Alternating)
96 subjects Participants
6 weeks Treatment Period

2/100 Hz alternating electroacupuncture demonstrates superior efficacy over single-frequency stimulation in tinnitus symptom alleviation and brain activity normalization.

View Source 2024
RCT ENT Disorders

Comparison of Frequency-Specific Effects of Electroacupuncture (2 Hz/100 Hz Alternating) for Tinnitus: A Randomized Controlled Trial

Im JH, Choi GH, Lee TY, et al. Neuromodulation (2024)
48% THI Reduction (Alternating)
96 subjects Participants
6 weeks Treatment Period

Summary

Ninety-six patients with chronic tinnitus were assigned to 2 Hz electroacupuncture, 100 Hz electroacupuncture, or 2/100 Hz alternating groups for 6 weeks of treatment. The 2/100 Hz alternating group demonstrated a 48% reduction in THI, significantly superior to the 2 Hz (31%) and 100 Hz (35%) groups. Auditory cortex hyperactivity on fMRI also showed the greatest reduction in the alternating group.

Key Conclusion

2/100 Hz alternating electroacupuncture demonstrates superior efficacy over single-frequency stimulation in tinnitus symptom alleviation and brain activity normalization.

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Before-After ENT Disorders

Korean Medicine Combination Treatment for Residual Symptoms After Chronic Sinusitis Surgery: A Pre-Post Comparison Study

이건호, 김미소, 조원빈, et al.

한방안이비인후피부과학회지 (2023)

44% SNOT-22 improvement rate
36 patients Study population
8 weeks Treatment duration

Korean medicine combination treatment is effective for managing residual symptoms after sinus surgery and may contribute to reducing reoperation rates.

View Source 2023
Before-After ENT Disorders

Korean Medicine Combination Treatment for Residual Symptoms After Chronic Sinusitis Surgery: A Pre-Post Comparison Study

이건호, 김미소, 조원빈, et al. 한방안이비인후피부과학회지 (2023)
44% SNOT-22 improvement rate
36 patients Study population
8 weeks Treatment duration

Summary

A pre-post comparison study performing 8 weeks of herbal medicine (modified Hyeonggaeyeongyo-tang), acupuncture, and nasal fumigation in 36 patients with residual symptoms persisting more than 6 months after endoscopic sinus surgery (ESS). SNOT-22 scores improved by an average of 44%, with reduced mucosal edema and discharge on nasal endoscopy.

Key Conclusion

Korean medicine combination treatment is effective for managing residual symptoms after sinus surgery and may contribute to reducing reoperation rates.

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RCT ENT Disorders

Effect of Combined Nasal Pharmacopuncture and Acupuncture for Nasal Obstruction in Chronic Rhinitis: A Randomized Controlled Trial

김태은, 이준석, 박가현, et al.

Rhinology (2024)

52% NOSE score improvement
88 patients Study population
8 weeks Treatment duration

Combined nasal pharmacopuncture and acupuncture shows effects equivalent to nasal steroids for chronic rhinitis nasal obstruction and is an alternative that can reduce steroid use.

View Source 2024
RCT ENT Disorders

Effect of Combined Nasal Pharmacopuncture and Acupuncture for Nasal Obstruction in Chronic Rhinitis: A Randomized Controlled Trial

김태은, 이준석, 박가현, et al. Rhinology (2024)
52% NOSE score improvement
88 patients Study population
8 weeks Treatment duration

Summary

A randomized controlled trial comparing nasal pharmacopuncture (Magnolia-Xanthium extract) plus acupuncture combination group versus nasal steroid alone group in 88 patients with nasal obstruction due to chronic rhinitis. After 8 weeks, NOSE (Nasal Obstruction Assessment) scores significantly improved in the combination group, with equivalent rhinomanometry results.

Key Conclusion

Combined nasal pharmacopuncture and acupuncture shows effects equivalent to nasal steroids for chronic rhinitis nasal obstruction and is an alternative that can reduce steroid use.

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Cross-Sectional ENT Disorders

Effect of Thread Embedding Therapy for Facial Nerve Palsy Sequelae: A Cross-Sectional Study

Choi AR, Kim SH, Yoo HR, et al.

Journal of Clinical Medicine (2023)

21 points Sunnybrook Improvement
78% Patient Satisfaction
62 subjects Participants

Thread embedding therapy is an effective Korean medicine procedure for both facial function and aesthetic improvement in facial nerve palsy sequelae.

View Source 2023
Cross-Sectional ENT Disorders

Effect of Thread Embedding Therapy for Facial Nerve Palsy Sequelae: A Cross-Sectional Study

Choi AR, Kim SH, Yoo HR, et al. Journal of Clinical Medicine (2023)
21 points Sunnybrook Improvement
78% Patient Satisfaction
62 subjects Participants

Summary

Sixty-two patients with sequelae (synkinesis, facial contracture) persisting more than 3 months after Bell's palsy received thread embedding therapy, with Sunnybrook facial grading and patient satisfaction evaluated. After 8 weeks of treatment, Sunnybrook scores improved by an average of 21 points, with facial symmetry satisfaction reaching 78%.

Key Conclusion

Thread embedding therapy is an effective Korean medicine procedure for both facial function and aesthetic improvement in facial nerve palsy sequelae.

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