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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 91 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Before-After Digestive Disorders

Gastrointestinal Motility Promotion Effect of Moxibustion for Digestive Diseases

Shin JC, Hwang MS, Park SU, et al.

Complementary Therapies in Medicine (2023)

28% Gastric Emptying Improvement Rate
45 subjects Number of Participants

Moxibustion promotes gastrointestinal motility and contributes to functional dyspepsia improvement.

View Source 2023
Before-After Digestive Disorders

Gastrointestinal Motility Promotion Effect of Moxibustion for Digestive Diseases

Shin JC, Hwang MS, Park SU, et al. Complementary Therapies in Medicine (2023)
28% Gastric Emptying Improvement Rate
45 subjects Number of Participants

Summary

Gastric emptying time before and after moxibustion treatment at Zusanli (ST36) was measured by ultrasound in 45 patients with functional dyspepsia. After moxibustion treatment, gastric half-emptying time was shortened by an average of 28%.

Key Conclusion

Moxibustion promotes gastrointestinal motility and contributes to functional dyspepsia improvement.

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RCT Digestive Disorders

Treatment Effect of Sogeonjung-tang for Chronic Gastritis and Gastric Mucosal Protection Mechanism

Park JM, Han YM, Oh JY, et al.

Phytomedicine (2021)

67% Inflammation Improvement Rate
55 subjects Number of Participants

Sogeonjung-tang is effective for chronic gastritis treatment through gastric mucosal protection mechanisms.

View Source 2021
RCT Digestive Disorders

Treatment Effect of Sogeonjung-tang for Chronic Gastritis and Gastric Mucosal Protection Mechanism

Park JM, Han YM, Oh JY, et al. Phytomedicine (2021)
67% Inflammation Improvement Rate
55 subjects Number of Participants

Summary

Sogeonjung-tang was administered for 12 weeks to 55 patients with chronic gastritis, and endoscopic findings and H. pylori status were evaluated. Gastric mucosal inflammation grade improved by 67%, and gastric mucosal defense factor (PGE2) secretion increased.

Key Conclusion

Sogeonjung-tang is effective for chronic gastritis treatment through gastric mucosal protection mechanisms.

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Cohort Study Digestive Disorders

Combined Acupuncture and Herbal Medicine Treatment and Quality of Life Changes in IBS Patients: A Cohort Study

Song MY, Cho SH, Kim JA, et al.

Journal of Korean Medicine (2024)

41 points IBS-QOL Improvement
80 subjects Number of Participants

Combined acupuncture and herbal medicine treatment more effectively improves quality of life in IBS patients than monotherapy.

View Source 2024
Cohort Study Digestive Disorders

Combined Acupuncture and Herbal Medicine Treatment and Quality of Life Changes in IBS Patients: A Cohort Study

Song MY, Cho SH, Kim JA, et al. Journal of Korean Medicine (2024)
41 points IBS-QOL Improvement
80 subjects Number of Participants

Summary

Eighty IBS patients were divided into an acupuncture monotherapy group, a herbal medicine monotherapy group, and an acupuncture-herbal medicine combined group, and followed for 12 weeks. The combined group showed a 41-point improvement in IBS-QOL scores, significantly higher than the monotherapy groups (acupuncture 28 points, herbal medicine 31 points).

Key Conclusion

Combined acupuncture and herbal medicine treatment more effectively improves quality of life in IBS patients than monotherapy.

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Systematic Review Digestive Disorders

GERD Recurrence Prevention Effect of Korean Medicine Treatment: A Systematic Review

Yoo HJ, Lee SG, Kim HY, et al.

BMC Complementary Medicine and Therapies (2022)

18% Recurrence Rate
16 studies Number of Reviewed Studies

Korean medicine treatment is effective for GERD recurrence prevention and may serve as an alternative to long-term PPI use.

View Source 2022
Systematic Review Digestive Disorders

GERD Recurrence Prevention Effect of Korean Medicine Treatment: A Systematic Review

Yoo HJ, Lee SG, Kim HY, et al. BMC Complementary Medicine and Therapies (2022)
18% Recurrence Rate
16 studies Number of Reviewed Studies

Summary

The effect of Korean medicine treatment for preventing recurrence of gastroesophageal reflux disease (GERD) was systematically analyzed across 16 studies. The 6-month recurrence rate of the herbal medicine maintenance treatment group was 18%, significantly lower than the PPI discontinuation group (42%).

Key Conclusion

Korean medicine treatment is effective for GERD recurrence prevention and may serve as an alternative to long-term PPI use.

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Before-After Digestive Disorders

Effect of Electroacupuncture on Gastric Accommodation in Functional Dyspepsia Patients

Jung HK, Choi MG, Lim CH, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

23% Accommodation Volume Increase
40 subjects Number of Participants

Electroacupuncture corrects the core pathophysiology of functional dyspepsia by improving gastric accommodation.

View Source 2023
Before-After Digestive Disorders

Effect of Electroacupuncture on Gastric Accommodation in Functional Dyspepsia Patients

Jung HK, Choi MG, Lim CH, et al. Evidence-Based Complementary and Alternative Medicine (2023)
23% Accommodation Volume Increase
40 subjects Number of Participants

Summary

Gastric accommodation before and after electroacupuncture treatment was measured by barostat in 40 patients with functional dyspepsia. After electroacupuncture, gastric accommodation volume increased by an average of 23%, with improvement in postprandial discomfort.

Key Conclusion

Electroacupuncture corrects the core pathophysiology of functional dyspepsia by improving gastric accommodation.

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Meta-Analysis Digestive Disorders

Meta-Analysis of Treatment Effect of Sagunja-tang Modifications for Functional Dyspepsia

Kwon SJ, Bae KH, Lee BH, et al.

Complementary Therapies in Medicine (2024)

RR 1.38 Relative Risk
14 studies Number of Reviewed RCTs

Sagunja-tang modifications demonstrate significant effects for functional dyspepsia treatment with a moderate level of evidence.

View Source 2024
Meta-Analysis Digestive Disorders

Meta-Analysis of Treatment Effect of Sagunja-tang Modifications for Functional Dyspepsia

Kwon SJ, Bae KH, Lee BH, et al. Complementary Therapies in Medicine (2024)
RR 1.38 Relative Risk
14 studies Number of Reviewed RCTs

Summary

The functional dyspepsia treatment effect of Sagunja-tang and modifications was meta-analyzed across 14 RCTs. The symptom improvement rate of the Sagunja-tang group was significantly higher than the control group at RR 1.38 (95% CI: 1.21-1.58).

Key Conclusion

Sagunja-tang modifications demonstrate significant effects for functional dyspepsia treatment with a moderate level of evidence.

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RCT Digestive Disorders

Clinical Effect of Gwakhyangjeonggi-san for IBS-D Type: A Randomized Double-Blind Study

Oh MS, Choi DJ, Ryu BH, et al.

Journal of Ethnopharmacology (2023)

57% Bowel Movement Reduction
60 subjects Number of Participants

Gwakhyangjeonggi-san is effective for reducing bowel movement frequency and normalizing stool form in IBS-D.

View Source 2023
RCT Digestive Disorders

Clinical Effect of Gwakhyangjeonggi-san for IBS-D Type: A Randomized Double-Blind Study

Oh MS, Choi DJ, Ryu BH, et al. Journal of Ethnopharmacology (2023)
57% Bowel Movement Reduction
60 subjects Number of Participants

Summary

Sixty patients with diarrhea-type IBS (IBS-D) were divided into a Gwakhyangjeonggi-san group and a placebo group and treated for 8 weeks. The Gwakhyangjeonggi-san group showed bowel movements decreasing from an average of 4.2 times per day to 1.8 times, and the Bristol stool scale normalized.

Key Conclusion

Gwakhyangjeonggi-san is effective for reducing bowel movement frequency and normalizing stool form in IBS-D.

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Cohort Study Digestive Disorders

Study on Gut Microbiome Diversity Changes in Korean Medicine Digestive Treatment

Ko SG, Kang BK, Lee NR, et al.

Phytomedicine (2024)

50 subjects Number of Participants
34% Beneficial Bacteria Increase Rate

Herbal medicine treatment increases gut microbiome diversity and increases the proportion of beneficial bacteria, improving digestive health.

View Source 2024
Cohort Study Digestive Disorders

Study on Gut Microbiome Diversity Changes in Korean Medicine Digestive Treatment

Ko SG, Kang BK, Lee NR, et al. Phytomedicine (2024)
50 subjects Number of Participants
34% Beneficial Bacteria Increase Rate

Summary

Herbal medicine was administered for 8 weeks to 50 patients with digestive diseases, and the gut microbiome was evaluated by 16S rRNA analysis. After treatment, the Shannon diversity index increased significantly, and the proportion of beneficial bacteria (Lactobacillus, Bifidobacterium) improved.

Key Conclusion

Herbal medicine treatment increases gut microbiome diversity and increases the proportion of beneficial bacteria, improving digestive health.

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Before-After Digestive Disorders

Effect of Acupuncture on Esophageal Motility Improvement in Reflux Esophagitis

Han GJ, Park SJ, Lee HY, et al.

BMC Complementary Medicine and Therapies (2021)

31% LES Pressure Increase
35 subjects Number of Participants

Acupuncture strengthens lower esophageal sphincter function and contributes to reflux esophagitis improvement.

View Source 2021
Before-After Digestive Disorders

Effect of Acupuncture on Esophageal Motility Improvement in Reflux Esophagitis

Han GJ, Park SJ, Lee HY, et al. BMC Complementary Medicine and Therapies (2021)
31% LES Pressure Increase
35 subjects Number of Participants

Summary

Lower esophageal sphincter (LES) pressure and esophageal peristalsis before and after acupuncture treatment were measured by high-resolution esophageal manometry in 35 patients with reflux esophagitis. After acupuncture treatment, LES pressure increased by an average of 31%.

Key Conclusion

Acupuncture strengthens lower esophageal sphincter function and contributes to reflux esophagitis improvement.

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Cross-Sectional Digestive Disorders

Patient Satisfaction and Cost-Effectiveness Analysis of Korean Medicine Treatment for Dyspepsia

Jung WJ, Leem JT, Kim TH, et al.

Journal of Korean Medicine (2022)

4.2/5 Patient Satisfaction
500 subjects Number of Participants

Korean medicine treatment for dyspepsia shows higher patient satisfaction compared to Western medicine treatment and is cost-effective.

View Source 2022
Cross-Sectional Digestive Disorders

Patient Satisfaction and Cost-Effectiveness Analysis of Korean Medicine Treatment for Dyspepsia

Jung WJ, Leem JT, Kim TH, et al. Journal of Korean Medicine (2022)
4.2/5 Patient Satisfaction
500 subjects Number of Participants

Summary

Patient satisfaction and medical costs were comparatively analyzed between 250 patients receiving Korean medicine treatment and 250 patients receiving Western medicine treatment for dyspepsia. The satisfaction of the Korean medicine treatment group was 4.2/5 points, higher than the Western medicine treatment group (3.6/5 points), and total medical costs were similar.

Key Conclusion

Korean medicine treatment for dyspepsia shows higher patient satisfaction compared to Western medicine treatment and is cost-effective.

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RCT Digestive Disorders

Gastrointestinal Hormone Regulation Effect of Bojungikgi-tang in Functional Dyspepsia Treatment

Jeon YJ, Shin AS, Park YC, et al.

Evidence-Based Complementary and Alternative Medicine (2024)

26% Motilin Increase Rate
48 subjects Number of Participants

The mechanism of Bojungikgi-tang improving digestive function through gastrointestinal hormone regulation has been confirmed.

View Source 2024
RCT Digestive Disorders

Gastrointestinal Hormone Regulation Effect of Bojungikgi-tang in Functional Dyspepsia Treatment

Jeon YJ, Shin AS, Park YC, et al. Evidence-Based Complementary and Alternative Medicine (2024)
26% Motilin Increase Rate
48 subjects Number of Participants

Summary

Bojungikgi-tang was administered for 8 weeks to 48 patients with functional dyspepsia, and changes in gastrointestinal hormones including motilin, gastrin, and somatostatin were measured. After Bojungikgi-tang administration, motilin increased by 26% and gastrin normalized.

Key Conclusion

The mechanism of Bojungikgi-tang improving digestive function through gastrointestinal hormone regulation has been confirmed.

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Cohort Study Digestive Disorders

Long-Term Follow-Up Study of Korean Medicine Treatment for Irritable Bowel Syndrome Patients

Lim JY, Song JC, Kim BK, et al.

Complementary Therapies in Medicine (2022)

54% 24-Month Maintenance Rate
95 subjects Number of Participants

The effect of Korean medicine IBS treatment persists over the long term, with more than half of patients maintaining the effect for 2 years.

View Source 2022
Cohort Study Digestive Disorders

Long-Term Follow-Up Study of Korean Medicine Treatment for Irritable Bowel Syndrome Patients

Lim JY, Song JC, Kim BK, et al. Complementary Therapies in Medicine (2022)
54% 24-Month Maintenance Rate
95 subjects Number of Participants

Summary

Ninety-five IBS patients were followed for 24 months after Korean medicine treatment. Twelve months after treatment completion, 68% of patients maintained symptom improvement status, and at 24 months, 54% maintained it.

Key Conclusion

The effect of Korean medicine IBS treatment persists over the long term, with more than half of patients maintaining the effect for 2 years.

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