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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 44 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Case Study Geum! Maek! Capsule Diet

Adipocyte Differentiation Inhibition Mechanism of Herbal Medicine Extract: An in vitro Study

Roh SS, Jung AY, Kwon DY, et al.

Journal of Ethnopharmacology (2021)

68% Differentiation Inhibition Rate
3 types Major Herbal Materials

Herbal medicine extracts effectively block adipocyte differentiation through inhibition of key transcription factors.

View Source 2021
Case Study Geum! Maek! Capsule Diet

Adipocyte Differentiation Inhibition Mechanism of Herbal Medicine Extract: An in vitro Study

Roh SS, Jung AY, Kwon DY, et al. Journal of Ethnopharmacology (2021)
68% Differentiation Inhibition Rate
3 types Major Herbal Materials

Summary

The 3T3-L1 preadipocyte differentiation inhibition effect of a combined herbal medicine extract (Astragalus, Atractylodes, Alisma) was evaluated. The herbal medicine extract inhibited adipocyte differentiation by 68% by suppressing PPARγ and C/EBPα expression.

Key Conclusion

Herbal medicine extracts effectively block adipocyte differentiation through inhibition of key transcription factors.

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Cross-Sectional Geum! Maek! Capsule Diet

Korean Medicine Treatment Satisfaction and Quality of Life Changes in Obese Patients: A Multicenter Cross-Sectional Study

Ha NY, Shin JY, Choi WJ, et al.

Journal of Korean Medicine (2019)

4.1/5 Treatment Satisfaction
350 subjects Number of Participants

Korean medicine obesity treatment contributes to high patient satisfaction along with quality of life improvement.

View Source 2019
Cross-Sectional Geum! Maek! Capsule Diet

Korean Medicine Treatment Satisfaction and Quality of Life Changes in Obese Patients: A Multicenter Cross-Sectional Study

Ha NY, Shin JY, Choi WJ, et al. Journal of Korean Medicine (2019)
4.1/5 Treatment Satisfaction
350 subjects Number of Participants

Summary

Treatment satisfaction and SF-36 quality of life scores were analyzed in 350 patients receiving Korean medicine obesity treatment at 8 Korean medicine clinics. Overall satisfaction was 4.1/5 points, with significant improvements in physical function and mental health domains.

Key Conclusion

Korean medicine obesity treatment contributes to high patient satisfaction along with quality of life improvement.

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Cohort Study Geum! Maek! Capsule Diet

Effect of Maintenance Program for Yo-Yo Effect Prevention After Korean Medicine Obesity Treatment

Cho YJ, Kim TH, Sung HK, et al.

Complementary Therapies in Medicine (2024)

1.2kg Participant Group Regain
200 subjects Number of Participants

Korean medicine maintenance programs effectively prevent the yo-yo effect after obesity treatment.

View Source 2024
Cohort Study Geum! Maek! Capsule Diet

Effect of Maintenance Program for Yo-Yo Effect Prevention After Korean Medicine Obesity Treatment

Cho YJ, Kim TH, Sung HK, et al. Complementary Therapies in Medicine (2024)
1.2kg Participant Group Regain
200 subjects Number of Participants

Summary

One hundred patients participating in a weight maintenance program (monthly acupuncture + herbal tea) and 100 non-participants were compared for 6 months after Korean medicine obesity treatment. Weight regain in the maintenance program participants was 1.2 kg, significantly less than the non-participant group (4.8 kg).

Key Conclusion

Korean medicine maintenance programs effectively prevent the yo-yo effect after obesity treatment.

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RCT Geum! Maek! Capsule Diet

Metabolic Improvement Effect of Moxibustion for Obesity: A Randomized Controlled Trial

Jang MK, Park HJ, Lee SD, et al.

BMC Complementary Medicine and Therapies (2020)

19% HOMA-IR Reduction
50 subjects Number of Participants

Moxibustion has comprehensive effects on improving metabolic indicators in obese patients.

View Source 2020
RCT Geum! Maek! Capsule Diet

Metabolic Improvement Effect of Moxibustion for Obesity: A Randomized Controlled Trial

Jang MK, Park HJ, Lee SD, et al. BMC Complementary Medicine and Therapies (2020)
19% HOMA-IR Reduction
50 subjects Number of Participants

Summary

Fifty obese patients were divided into a moxibustion treatment group and a control group, and metabolic indicators were compared after 8 weeks of treatment. The moxibustion treatment group showed reductions in fasting blood glucose by 8%, triglycerides by 14%, and HOMA-IR by 19%.

Key Conclusion

Moxibustion has comprehensive effects on improving metabolic indicators in obese patients.

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Before-After Geum! Maek! Capsule Diet

Satiety Enhancement and Energy Intake Reduction Effect of Herbal Medicine Diet Capsules

Woo JS, Min BJ, Lim CY, et al.

Phytomedicine (2023)

320kcal Daily Intake Reduction
42 subjects Number of Participants

Herbal medicine diet capsules induce natural caloric intake reduction by increasing satiety.

View Source 2023
Before-After Geum! Maek! Capsule Diet

Satiety Enhancement and Energy Intake Reduction Effect of Herbal Medicine Diet Capsules

Woo JS, Min BJ, Lim CY, et al. Phytomedicine (2023)
320kcal Daily Intake Reduction
42 subjects Number of Participants

Summary

Herbal medicine diet capsules were administered for 6 weeks to 42 overweight adults, and food diaries and satiety scales were analyzed. After capsule administration, daily caloric intake decreased by an average of 320 kcal, and satiety increased by 35%.

Key Conclusion

Herbal medicine diet capsules induce natural caloric intake reduction by increasing satiety.

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Meta-Analysis Geum! Maek! Capsule Diet

Effect of Herbal Medicine Treatment on Inflammatory Markers in Obese Patients: A Meta-Analysis

Park SJ, Hong JM, Kim YS, et al.

Journal of Ethnopharmacology (2025)

SMD -0.89 CRP Reduction Effect
13 studies Number of Reviewed RCTs

Korean herbal medicine obesity treatment significantly reduces systemic inflammation along with weight loss.

View Source 2025
Meta-Analysis Geum! Maek! Capsule Diet

Effect of Herbal Medicine Treatment on Inflammatory Markers in Obese Patients: A Meta-Analysis

Park SJ, Hong JM, Kim YS, et al. Journal of Ethnopharmacology (2025)
SMD -0.89 CRP Reduction Effect
13 studies Number of Reviewed RCTs

Summary

The effect of Korean herbal medicine obesity treatment on inflammatory markers (CRP, IL-6, TNF-α) was meta-analyzed across 13 RCTs. The herbal medicine group showed significant reductions in CRP (SMD: -0.89) and IL-6 (SMD: -0.74).

Key Conclusion

Korean herbal medicine obesity treatment significantly reduces systemic inflammation along with weight loss.

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Cross-Sectional Geum! Maek! Capsule Diet

Effect of Korean Medicine Diet on Weight Management in Postmenopausal Women: A Cross-Sectional Study

Yoon SH, Kim MJ, Han CH, et al.

Journal of Korean Medicine (2021)

5.4kg Average Weight Loss
72 subjects Number of Participants

Korean medicine diet selectively reduces body fat while preserving bone mineral density in postmenopausal women.

View Source 2021
Cross-Sectional Geum! Maek! Capsule Diet

Effect of Korean Medicine Diet on Weight Management in Postmenopausal Women: A Cross-Sectional Study

Yoon SH, Kim MJ, Han CH, et al. Journal of Korean Medicine (2021)
5.4kg Average Weight Loss
72 subjects Number of Participants

Summary

Weight, body fat, and bone mineral density before and after participation in a Korean medicine diet program were comparatively analyzed in 72 postmenopausal obese women. An average weight reduction of 5.4 kg was achieved, with selective body fat reduction without bone mineral density loss.

Key Conclusion

Korean medicine diet selectively reduces body fat while preserving bone mineral density in postmenopausal women.

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Cohort Study Geum! Maek! Capsule Diet

Liver Function Safety Evaluation of Korean Medicine Obesity Treatment: A Prospective Monitoring Study

Shin IS, Ko SG, Lee MY, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

97.5% Normal Maintenance Rate
200 subjects Number of Participants

Korean medicine obesity treatment is safe for liver function and shows positive effects on existing fatty liver improvement.

View Source 2022
Cohort Study Geum! Maek! Capsule Diet

Liver Function Safety Evaluation of Korean Medicine Obesity Treatment: A Prospective Monitoring Study

Shin IS, Ko SG, Lee MY, et al. Evidence-Based Complementary and Alternative Medicine (2022)
97.5% Normal Maintenance Rate
200 subjects Number of Participants

Summary

Liver function (AST, ALT, GGT) changes were prospectively monitored for 12 weeks in 200 patients receiving Korean medicine obesity treatment. Liver function values remained within the normal range in 97.5% of patients, and the fatty liver index actually improved.

Key Conclusion

Korean medicine obesity treatment is safe for liver function and shows positive effects on existing fatty liver improvement.

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RCT Geum! Maek! Capsule Diet

Effect of Korean Medicine Treatment for Pediatric Obesity: A Randomized Controlled Trial

Choi SH, Lee JA, Park BK, et al.

Complementary Therapies in Medicine (2023)

0.42 BMI z-score Reduction
60 subjects Number of Participants

Korean medicine obesity treatment can be safely and effectively applied to pediatric obesity.

View Source 2023
RCT Geum! Maek! Capsule Diet

Effect of Korean Medicine Treatment for Pediatric Obesity: A Randomized Controlled Trial

Choi SH, Lee JA, Park BK, et al. Complementary Therapies in Medicine (2023)
0.42 BMI z-score Reduction
60 subjects Number of Participants

Summary

Sixty obese children aged 8-15 were divided into a Korean medicine treatment group and a nutrition education control group and treated for 12 weeks. The Korean medicine group showed a BMI z-score reduction of 0.42, with a 3.1% reduction in body fat percentage.

Key Conclusion

Korean medicine obesity treatment can be safely and effectively applied to pediatric obesity.

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Systematic Review Geum! Maek! Capsule Diet

Effect of Korean Medicine Dietary Therapy for Obesity Treatment: A Systematic Review

Bae GS, Jang JG, Oh TW, et al.

BMC Complementary Medicine and Therapies (2022)

20 studies Number of Reviewed Studies
34% Additional Weight Loss Effect

Korean medicine dietary therapy is an adjunctive strategy that significantly enhances obesity treatment effects.

View Source 2022
Systematic Review Geum! Maek! Capsule Diet

Effect of Korean Medicine Dietary Therapy for Obesity Treatment: A Systematic Review

Bae GS, Jang JG, Oh TW, et al. BMC Complementary Medicine and Therapies (2022)
20 studies Number of Reviewed Studies
34% Additional Weight Loss Effect

Summary

The obesity treatment effect of Korean medicine dietary therapy (medicinal cuisine, herbal tea, constitution-specific diet) was systematically analyzed across 20 studies. When Korean medicine dietary therapy was combined, the average weight reduction rate was 34% higher.

Key Conclusion

Korean medicine dietary therapy is an adjunctive strategy that significantly enhances obesity treatment effects.

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Narrative Review Geum! Maek! Capsule Diet

Review of Preclinical Studies on Brown Fat Activation Effect of Herbal Medicine

Nam HJ, Lee BH, Kang OS, et al.

Phytomedicine (2024)

17 studies Number of Reviewed Studies
5 types Major Herbal Materials

Herbal medicine components increase energy expenditure through brown fat activation, presenting a new mechanism for obesity treatment.

View Source 2024
Narrative Review Geum! Maek! Capsule Diet

Review of Preclinical Studies on Brown Fat Activation Effect of Herbal Medicine

Nam HJ, Lee BH, Kang OS, et al. Phytomedicine (2024)
17 studies Number of Reviewed Studies
5 types Major Herbal Materials

Summary

The effect of herbal medicine components on brown adipose tissue (BAT) activation was analyzed across 17 animal experiments. Herbal medicine components such as cinnamon, ginger, and aconite were shown to increase UCP1 expression and promote thermogenesis.

Key Conclusion

Herbal medicine components increase energy expenditure through brown fat activation, presenting a new mechanism for obesity treatment.

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Cohort Study Geum! Maek! Capsule Diet

Importance of Combined Lifestyle Modification in Korean Medicine Obesity Treatment: A Multicenter Cohort Study

Kim BJ, Choi IH, Yun YH, et al.

Journal of Korean Medicine (2024)

9.1kg Combined Group Weight Loss
240 subjects Number of Participants

Combining lifestyle modification with Korean medicine obesity treatment improves weight loss effects by approximately 60%.

View Source 2024
Cohort Study Geum! Maek! Capsule Diet

Importance of Combined Lifestyle Modification in Korean Medicine Obesity Treatment: A Multicenter Cohort Study

Kim BJ, Choi IH, Yun YH, et al. Journal of Korean Medicine (2024)
9.1kg Combined Group Weight Loss
240 subjects Number of Participants

Summary

At 6 Korean medicine clinics, 16-week treatment outcomes were compared between a herbal medicine + acupuncture group (120 subjects) and a herbal medicine + acupuncture + lifestyle modification group (120 subjects). The lifestyle combined group showed significantly greater weight reduction (9.1 kg vs 5.7 kg).

Key Conclusion

Combining lifestyle modification with Korean medicine obesity treatment improves weight loss effects by approximately 60%.

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