Meta-Analysis of Anti-Stress Effects of Gyeongokgo and HPA Axis Regulation Mechanisms
Journal · Stress (2025)
Original authors · Yun YJ, Koo BS, Lee JE, et al.
DOI · 10.1080/10253890.2025.2298741
Summary
A meta-analysis of 22 clinical and preclinical studies investigating the stress response regulation effect of Gyeongokgo. Reduction in serum cortisol, ACTH regulation, and hippocampal neuroprotective effects were consistently reported.
Key figures
Studies Analyzed
22 studies
HPA Axis Regulation
Cortisol 29% reduction
Overall Effect Size
ES=0.68
Conclusion
Gyeongokgo demonstrates anti-stress effects through HPA axis regulation and can be utilized as a complementary treatment for stress-related conditions.
The summary, conclusion and key figures on this page were prepared by Geum Maek Korean Medical Clinic. Copyright of the original paper belongs to its authors, and the full text is not reproduced here. The original is available on the publisher page.
Findings were observed under specific study conditions and results may differ by individual. This does not replace medical consultation.