It is possible, and saying this part in advance matters.

Early in taking it there are cases where itching increases or the rash spreads temporarily. However, we do not explain this unconditionally as a 'healing reaction'. That is because it may also be a reaction appearing because the medicine does not suit you.

So please do not endure it and keep taking it on your own — be sure to tell us. We look at the state and judge whether to adjust the prescription or stop it.

The following require you to stop immediately and contact us: hives spreading over the whole body, swelling of the face or lips, uncomfortable breathing, blisters forming, or a rash spreading with fever. It may be a drug allergy reaction.

If the skin lesion weeps and yellow crusting forms, a bacterial infection may have been added, so dermatology care is needed.