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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 71 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Respiratory Conditions

Combined Herbal Medicine and Pediatric Chuna Treatment for Recurrent Upper Respiratory Infections in Children: A Cohort Study

조미영, 박건우, 김서연, et al.

대한한방소아과학회지 (2024)

58% Infection frequency reduction
72 patients Study population
41% Antibiotic use reduction

Combined herbal medicine and pediatric Chuna treatment is an effective Korean medicine management method that reduces both illness frequency and antibiotic use in children with recurrent upper respiratory infections.

View Source 2024
Cohort Study Respiratory Conditions

Combined Herbal Medicine and Pediatric Chuna Treatment for Recurrent Upper Respiratory Infections in Children: A Cohort Study

조미영, 박건우, 김서연, et al. 대한한방소아과학회지 (2024)
58% Infection frequency reduction
72 patients Study population
41% Antibiotic use reduction

Summary

A prospective cohort study performing 6 months of combined herbal medicine (modified Samso-eum) and pediatric Chuna in 72 children aged 3-8 years with recurrent upper respiratory infections (6 or more annually). Upper respiratory infections decreased by an average of 58% during treatment period, with significantly reduced antibiotic use days.

Key Conclusion

Combined herbal medicine and pediatric Chuna treatment is an effective Korean medicine management method that reduces both illness frequency and antibiotic use in children with recurrent upper respiratory infections.

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Meta-Analysis Respiratory Conditions

Meta-Analysis of Herbal Medicine Treatment Efficacy for Pulmonary Fibrosis Patients

김현우, 이나영, 정태섭, et al.

Journal of Integrative Medicine (2023)

2.8% FVC decline attenuation
8 studies Analyzed studies
612 patients Total study population

Herbal medicine treatment can play an adjunctive role in slowing pulmonary fibrosis progression and improving quality of life, with notable potential for combination with antifibrotic agents.

View Source 2023
Meta-Analysis Respiratory Conditions

Meta-Analysis of Herbal Medicine Treatment Efficacy for Pulmonary Fibrosis Patients

김현우, 이나영, 정태섭, et al. Journal of Integrative Medicine (2023)
2.8% FVC decline attenuation
8 studies Analyzed studies
612 patients Total study population

Summary

Eight RCTs (total 612 patients) evaluating herbal medicine treatment for idiopathic pulmonary fibrosis (IPF) were meta-analyzed. The herbal medicine combination group showed 2.8% annual FVC decline rate attenuation, with significantly improved SGRQ (respiratory quality of life) scores.

Key Conclusion

Herbal medicine treatment can play an adjunctive role in slowing pulmonary fibrosis progression and improving quality of life, with notable potential for combination with antifibrotic agents.

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Case Study Respiratory Conditions

Effects of Herbal Medicine Adjuvant Treatment in Bronchiectasis Patients: A Case Series of 12 Cases

정가은, 김민수, 박윤아, et al.

한방재활의학과학회지 (2024)

54% Sputum volume reduction
12 patients Number of cases
12 weeks Treatment duration

Cheonggumganghwa-tang shows potential as adjunctive treatment for sputum reduction and acute exacerbation prevention in bronchiectasis patients.

View Source 2024
Case Study Respiratory Conditions

Effects of Herbal Medicine Adjuvant Treatment in Bronchiectasis Patients: A Case Series of 12 Cases

정가은, 김민수, 박윤아, et al. 한방재활의학과학회지 (2024)
54% Sputum volume reduction
12 patients Number of cases
12 weeks Treatment duration

Summary

A case series administering Cheonggumganghwa-tang for 12 weeks to 12 patients diagnosed with bronchiectasis. After treatment, daily sputum volume decreased by an average of 54%, with reduced acute exacerbation frequency and decreased hospitalizations. Bronchial wall thickening on chest CT also partially improved.

Key Conclusion

Cheonggumganghwa-tang shows potential as adjunctive treatment for sputum reduction and acute exacerbation prevention in bronchiectasis patients.

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RCT Respiratory Conditions

Immune-Enhancing Effect of Herbal Medicine for Influenza Prevention: A Randomized Controlled Trial

이윤호, 김소라, 박종민, et al.

Influenza and Other Respiratory Viruses (2023)

38% ILI occurrence reduction
180 patients Study population
1.6 days Symptom duration reduction

Modified Ssanghwa-tang shows potential as a preventive immune-enhancing agent during influenza epidemic season, and additional research targeting high-risk groups is needed.

View Source 2023
RCT Respiratory Conditions

Immune-Enhancing Effect of Herbal Medicine for Influenza Prevention: A Randomized Controlled Trial

이윤호, 김소라, 박종민, et al. Influenza and Other Respiratory Viruses (2023)
38% ILI occurrence reduction
180 patients Study population
1.6 days Symptom duration reduction

Summary

A randomized controlled trial comparing 8-week administration of modified Ssanghwa-tang versus placebo in 180 healthy adults during influenza epidemic season. The herbal medicine group showed 38% lower influenza-like illness (ILI) occurrence rate, with average 1.6-day shorter symptom duration when illness occurred.

Key Conclusion

Modified Ssanghwa-tang shows potential as a preventive immune-enhancing agent during influenza epidemic season, and additional research targeting high-risk groups is needed.

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Meta-Analysis Respiratory Conditions

Systematic Review and Meta-Analysis of Herbal Medicine Maintenance Treatment for Stable-Phase COPD Patients

정민재, 김도현, 박소연, et al.

Chronic Respiratory Disease (2023)

0.8 episodes Annual exacerbation reduction
15 studies Analyzed studies
33% Hospitalization rate reduction

Herbal medicine maintenance treatment shows significant effects on acute exacerbation prevention and hospitalization rate reduction in stable-phase COPD patients and may be included in long-term management strategies.

View Source 2023
Meta-Analysis Respiratory Conditions

Systematic Review and Meta-Analysis of Herbal Medicine Maintenance Treatment for Stable-Phase COPD Patients

정민재, 김도현, 박소연, et al. Chronic Respiratory Disease (2023)
0.8 episodes Annual exacerbation reduction
15 studies Analyzed studies
33% Hospitalization rate reduction

Summary

A meta-analysis of 15 RCTs (total 1,378 patients) evaluating acute exacerbation prevention effects of herbal medicine maintenance treatment for stable-phase COPD patients. The herbal medicine maintenance treatment group showed 0.8-fewer annual acute exacerbations, with 33% lower hospitalization rate.

Key Conclusion

Herbal medicine maintenance treatment shows significant effects on acute exacerbation prevention and hospitalization rate reduction in stable-phase COPD patients and may be included in long-term management strategies.

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RCT Respiratory Conditions

Herbal Medicine Treatment for Immunity Enhancement After Pediatric Respiratory Infections: A Randomized Controlled Trial

김보경, 이상현, 조해인, et al.

Pediatric Allergy and Immunology (2024)

45% Reinfection rate reduction
84 patients Study population
IgA increase Immune indicator improvement

Samchulgeonbi-tang is an effective herbal medicine prescription that promotes immunity recovery after pediatric respiratory infections and prevents reinfection.

View Source 2024
RCT Respiratory Conditions

Herbal Medicine Treatment for Immunity Enhancement After Pediatric Respiratory Infections: A Randomized Controlled Trial

김보경, 이상현, 조해인, et al. Pediatric Allergy and Immunology (2024)
45% Reinfection rate reduction
84 patients Study population
IgA increase Immune indicator improvement

Summary

A comparison of 8-week administration of Samchulgeonbi-tang versus vitamin control in 84 children aged 4-10 years suspected of immune decline after respiratory infection. The herbal medicine group showed 45% reduction in subsequent infection occurrence, with significant increases in salivary IgA and blood lymphocyte counts.

Key Conclusion

Samchulgeonbi-tang is an effective herbal medicine prescription that promotes immunity recovery after pediatric respiratory infections and prevents reinfection.

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Cohort Study Respiratory Conditions

Herbal Medicine Preventive Effect on Respiratory Symptoms in Residents of Particulate Matter Exposure Areas: A Cohort Study

박세진, 김하윤, 이병규, et al.

대한예방한의학회지 (2023)

28 days Symptom days reduction
214 patients Study population
12 months Follow-up period

Intermittent herbal medicine administration is an effective preventive strategy for respiratory health protection in residents of high particulate matter exposure areas.

View Source 2023
Cohort Study Respiratory Conditions

Herbal Medicine Preventive Effect on Respiratory Symptoms in Residents of Particulate Matter Exposure Areas: A Cohort Study

박세진, 김하윤, 이병규, et al. 대한예방한의학회지 (2023)
28 days Symptom days reduction
214 patients Study population
12 months Follow-up period

Summary

A cohort study following 214 adults residing in areas with high annual average particulate matter concentration for 12 months, comparing intermittent 4-week Cheongpyesagan-tang administration versus non-administration. The herbal medicine group showed average 28-day annual reduction in respiratory symptom days, with attenuated pulmonary function decline rate.

Key Conclusion

Intermittent herbal medicine administration is an effective preventive strategy for respiratory health protection in residents of high particulate matter exposure areas.

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Meta-Analysis Respiratory Conditions

Meta-Analysis of Herbal Medicine Treatment for Acute Bronchitis: Antibiotic Combination vs. Herbal Medicine Alone

정현우, 김선아, 박영준, et al.

Frontiers in Pharmacology (2023)

11 studies Analyzed studies
924 patients Total study population
Non-inferior Herbal medicine alone effect

Herbal medicine shows effective treatment results as monotherapy without antibiotics in mild acute bronchitis and may contribute to appropriate antibiotic use.

View Source 2023
Meta-Analysis Respiratory Conditions

Meta-Analysis of Herbal Medicine Treatment for Acute Bronchitis: Antibiotic Combination vs. Herbal Medicine Alone

정현우, 김선아, 박영준, et al. Frontiers in Pharmacology (2023)
11 studies Analyzed studies
924 patients Total study population
Non-inferior Herbal medicine alone effect

Summary

A meta-analysis of 11 RCTs (total 924 patients) analyzing herbal medicine treatment for acute bronchitis divided into antibiotic combination and herbal medicine alone groups. Both groups showed significant symptom improvement, with the herbal medicine alone group showing non-inferior cough resolution rate to the antibiotic combination group.

Key Conclusion

Herbal medicine shows effective treatment results as monotherapy without antibiotics in mild acute bronchitis and may contribute to appropriate antibiotic use.

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Systematic Review Respiratory Conditions

Systematic Review on Effects of Moxibustion Treatment for Asthmatic Children

한도윤, 정수빈, 김영민, et al.

Journal of Traditional Chinese Medicine (2024)

7 studies Analyzed studies
486 patients Total study population
PEFR increase Pulmonary function improvement trend

Moxibustion treatment is promising as an adjunctive treatment for pediatric asthma, but standardized treatment protocols and high-quality clinical trials are needed.

View Source 2024
Systematic Review Respiratory Conditions

Systematic Review on Effects of Moxibustion Treatment for Asthmatic Children

한도윤, 정수빈, 김영민, et al. Journal of Traditional Chinese Medicine (2024)
7 studies Analyzed studies
486 patients Total study population
PEFR increase Pulmonary function improvement trend

Summary

Seven clinical studies (total 486 patients) evaluating moxibustion treatment for pediatric asthma were systematically reviewed. The moxibustion group performed at GV14, BL13, CV22 showed decreasing trends in asthma attack frequency and improving PEFR, but heterogeneity between studies was high.

Key Conclusion

Moxibustion treatment is promising as an adjunctive treatment for pediatric asthma, but standardized treatment protocols and high-quality clinical trials are needed.

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RCT Respiratory Conditions

Antioxidant Effect of Jaeumganghwa-tang in Pulmonary Fibrosis Progression Suppression: A Randomized Controlled Trial

이민경, 김도영, 조서연, et al.

Oxidative Medicine and Cellular Longevity (2024)

34% MDA level reduction
66 patients Study population
24 weeks Treatment duration

Jaeumganghwa-tang shows adjunctive therapeutic effects suppressing pulmonary fibrosis progression through antioxidant mechanisms.

View Source 2024
RCT Respiratory Conditions

Antioxidant Effect of Jaeumganghwa-tang in Pulmonary Fibrosis Progression Suppression: A Randomized Controlled Trial

이민경, 김도영, 조서연, et al. Oxidative Medicine and Cellular Longevity (2024)
34% MDA level reduction
66 patients Study population
24 weeks Treatment duration

Summary

A 24-week randomized controlled trial comparing pirfenidone plus Jaeumganghwa-tang versus pirfenidone alone in 66 patients with mild-to-moderate pulmonary fibrosis. The herbal medicine combination group showed significant reductions in blood oxidative stress markers (MDA, 8-OHdG), with attenuated DLCO (diffusion capacity) decline rate.

Key Conclusion

Jaeumganghwa-tang shows adjunctive therapeutic effects suppressing pulmonary fibrosis progression through antioxidant mechanisms.

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Cross-Sectional Respiratory Conditions

Cost-Effectiveness Analysis of Korean Medicine Treatment for Respiratory Diseases: A Cross-Sectional Study

박지혜, 김승현, 이유리, et al.

대한한의학회지 (2023)

23% Medical cost reduction
312 patients Study population
0.12 points EQ-5D improvement

Korean medicine treatment for respiratory diseases is cost-effective and can simultaneously achieve medical cost reduction and quality of life improvement.

View Source 2023
Cross-Sectional Respiratory Conditions

Cost-Effectiveness Analysis of Korean Medicine Treatment for Respiratory Diseases: A Cross-Sectional Study

박지혜, 김승현, 이유리, et al. 대한한의학회지 (2023)
23% Medical cost reduction
312 patients Study population
0.12 points EQ-5D improvement

Summary

A cross-sectional study analyzing medical costs and quality of life data of 312 patients receiving Korean medicine treatment for respiratory diseases (asthma, rhinitis, bronchitis). Total medical costs decreased by an average of 23% in the year after starting Korean medicine treatment, with EQ-5D (quality of life) index improving by 0.12 points.

Key Conclusion

Korean medicine treatment for respiratory diseases is cost-effective and can simultaneously achieve medical cost reduction and quality of life improvement.

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Systematic Review Respiratory Conditions

Preventive Effect of Modified Okbyungpung-san for Children with Recurrent Upper Respiratory Tract Infections: A Systematic Review

한예진, 김주영, 정승민, et al.

Pediatric Infectious Disease Journal (2024)

9 studies Analyzed studies
742 patients Total study population
IgG/IgA increase Immune indicator improvement

Modified Okbyungpung-san is an effective herbal medicine prescription for immunity enhancement and infection prevention in children with RRTI, with sufficient evidence accumulating.

View Source 2024
Systematic Review Respiratory Conditions

Preventive Effect of Modified Okbyungpung-san for Children with Recurrent Upper Respiratory Tract Infections: A Systematic Review

한예진, 김주영, 정승민, et al. Pediatric Infectious Disease Journal (2024)
9 studies Analyzed studies
742 patients Total study population
IgG/IgA increase Immune indicator improvement

Summary

Nine clinical studies (total 742 patients) evaluating the preventive effect of modified Okbyungpung-san for children with recurrent respiratory tract infections (RRTI) were systematically reviewed. Most studies showed significantly reduced infection frequency in the Okbyungpung-san group, with reported IgG and IgA level elevations.

Key Conclusion

Modified Okbyungpung-san is an effective herbal medicine prescription for immunity enhancement and infection prevention in children with RRTI, with sufficient evidence accumulating.

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