금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 93 papers

Cross-Sectional ENT Disorders

Immediate and Sustained Effects of Nasal Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

이현주, 김수한, 정다빈, et al.

대한침구의학회지 (2023)

57.4% Nasal congestion VAS reduction
156 patients Study population
91% Patient satisfaction

Nasal pharmacopuncture treatment shows immediate relief effects for major symptoms of allergic rhinitis and is a treatment with high patient satisfaction.

Cross-Sectional ENT Disorders

Immediate and Sustained Effects of Nasal Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

이현주, 김수한, 정다빈, et al. 대한침구의학회지 (2023)
57.4% Nasal congestion VAS reduction
156 patients Study population
91% Patient satisfaction

Summary

A cross-sectional analysis of symptom changes before and after perinasal pharmacopuncture (Coptis-Schizonepeta extract) in 156 patients with allergic rhinitis. Nasal congestion VAS decreased from average 6.8 to 2.9 immediately after treatment, with significant improvements in sneeze frequency and rhinorrhea.

Key Conclusion

Nasal pharmacopuncture treatment shows immediate relief effects for major symptoms of allergic rhinitis and is a treatment with high patient satisfaction.

Before-After ENT Disorders

Antimicrobial and Anti-biofilm Activity Study of Changija-san in Chronic Sinusitis

Eom TK, Jung HJ, Kim MR, et al.

Journal of Ethnopharmacology (2023)

74.2% Biofilm Inhibition Rate
36 subjects Clinical Participants
83.3% Bacterial Conversion Rate

Changija-san possesses antimicrobial and anti-biofilm activity against chronic sinusitis pathogens and is also clinically useful.

Before-After ENT Disorders

Antimicrobial and Anti-biofilm Activity Study of Changija-san in Chronic Sinusitis

Eom TK, Jung HJ, Kim MR, et al. Journal of Ethnopharmacology (2023)
74.2% Biofilm Inhibition Rate
36 subjects Clinical Participants
83.3% Bacterial Conversion Rate

Summary

Antimicrobial and anti-biofilm activity of Changija-san extract against chronic sinusitis pathogens (S. aureus, P. aeruginosa) was evaluated through in vitro experiments. Changija-san demonstrated significant biofilm inhibition effects against both bacterial species. In 36 clinical patients, bacterial culture conversion rates were also high.

Key Conclusion

Changija-san possesses antimicrobial and anti-biofilm activity against chronic sinusitis pathogens and is also clinically useful.

Cross-Sectional ENT Disorders

Survey Study on Patient Satisfaction and Treatment Adherence in Korean Medicine Treatment for Rhinitis

Moon HW, Jang SB, Kwak MA, et al.

Journal of Korean Medicine (2024)

4.2/5 Patient Satisfaction
89.4% Treatment Adherence
320 subjects Participants

High patient satisfaction and adherence to Korean medicine treatment for rhinitis suggest that Korean medicine is a suitable approach for rhinitis management.

Cross-Sectional ENT Disorders

Survey Study on Patient Satisfaction and Treatment Adherence in Korean Medicine Treatment for Rhinitis

Moon HW, Jang SB, Kwak MA, et al. Journal of Korean Medicine (2024)
4.2/5 Patient Satisfaction
89.4% Treatment Adherence
320 subjects Participants

Summary

Three hundred twenty patients receiving Korean medicine treatment for rhinitis were surveyed on satisfaction and treatment adherence. Overall satisfaction was 4.2/5, and treatment adherence reached a high level of 89.4%.

Key Conclusion

High patient satisfaction and adherence to Korean medicine treatment for rhinitis suggest that Korean medicine is a suitable approach for rhinitis management.

RCT ENT Disorders

Randomized Controlled Trial of Combined Extracorporeal Shock Wave Acupuncture and Herbal Medicine for Allergic Rhinitis Patients

Ryu JK, Shin BC, Lee MS, et al.

Evidence-Based Complementary and Alternative Medicine (2021)

85.1% Combination Group Improvement Rate
94 subjects Participants
8 weeks Treatment Period

Combined extracorporeal shock wave acupuncture and herbal medicine enhances therapeutic efficacy in allergic rhinitis treatment.

RCT ENT Disorders

Randomized Controlled Trial of Combined Extracorporeal Shock Wave Acupuncture and Herbal Medicine for Allergic Rhinitis Patients

Ryu JK, Shin BC, Lee MS, et al. Evidence-Based Complementary and Alternative Medicine (2021)
85.1% Combination Group Improvement Rate
94 subjects Participants
8 weeks Treatment Period

Summary

Ninety-four patients with allergic rhinitis were assigned to extracorporeal shock wave acupuncture plus herbal medicine (47) or herbal medicine monotherapy (47) groups for 8 weeks. The combination group demonstrated significantly greater improvements in RQLQ scores and nasal endoscopic findings.

Key Conclusion

Combined extracorporeal shock wave acupuncture and herbal medicine enhances therapeutic efficacy in allergic rhinitis treatment.

Cross-Sectional ENT Disorders

Economic Analysis of Korean Medicine Treatment for ENT Diseases: Based on National Health Insurance Big Data

Jo JY, Hwang EH, Son CG, et al.

BMC Complementary Medicine and Therapies (2025)

23.7% Cost Reduction Rate
15,842 subjects Analyzed
6 years Analysis Period

In ENT diseases, Korean medicine treatment is cost-effective and may contribute to reduced healthcare utilization.

Cross-Sectional ENT Disorders

Economic Analysis of Korean Medicine Treatment for ENT Diseases: Based on National Health Insurance Big Data

Jo JY, Hwang EH, Son CG, et al. BMC Complementary Medicine and Therapies (2025)
23.7% Cost Reduction Rate
15,842 subjects Analyzed
6 years Analysis Period

Summary

Health insurance claims data from 2018-2023 were used to compare medical costs and reuse rates between Korean medicine and conventional medicine treatment for ENT diseases. The Korean medicine group demonstrated lower annual total medical costs and fewer revisits.

Key Conclusion

In ENT diseases, Korean medicine treatment is cost-effective and may contribute to reduced healthcare utilization.

Before-After ENT Disorders

Analysis of Quality-of-Life Changes Before and After Herbal Medicine Treatment in Postnasal Drip Syndrome Patients

Chae BY, Lim SC, Yoon HJ, et al.

Complementary Therapies in Medicine (2019)

67.3% SNOT-22 Improvement Rate
52 subjects Participants
p<0.001 SF-36 Improvement Significance

Herbal medicine treatment contributes not only to symptom improvement but also to overall quality-of-life enhancement in postnasal drip syndrome patients.

Before-After ENT Disorders

Analysis of Quality-of-Life Changes Before and After Herbal Medicine Treatment in Postnasal Drip Syndrome Patients

Chae BY, Lim SC, Yoon HJ, et al. Complementary Therapies in Medicine (2019)
67.3% SNOT-22 Improvement Rate
52 subjects Participants
p<0.001 SF-36 Improvement Significance

Summary

Fifty-two patients with postnasal drip syndrome received herbal medicine treatment for 8 weeks, with quality-of-life changes evaluated via SNOT-22 and SF-36 questionnaires. Significant improvements were confirmed in both questionnaires.

Key Conclusion

Herbal medicine treatment contributes not only to symptom improvement but also to overall quality-of-life enhancement in postnasal drip syndrome patients.

Systematic Review ENT Disorders

Combined Effect of Nasal Irrigation and Herbal Medicine for Rhinitis Treatment: A Systematic Review

Noh JH, Kim KS, Won JY, et al.

Phytomedicine (2022)

88.1% Combination Group Efficacy
10 papers Analyzed Papers
OR 2.34 Effect Size

Combination of nasal irrigation and herbal medicine demonstrates synergistic effects in rhinitis treatment.

Systematic Review ENT Disorders

Combined Effect of Nasal Irrigation and Herbal Medicine for Rhinitis Treatment: A Systematic Review

Noh JH, Kim KS, Won JY, et al. Phytomedicine (2022)
88.1% Combination Group Efficacy
10 papers Analyzed Papers
OR 2.34 Effect Size

Summary

Ten RCTs were analyzed to evaluate the combined effect of nasal irrigation and herbal medicine for rhinitis treatment. The combination group demonstrated superior symptom improvement compared with herbal medicine alone or nasal irrigation alone.

Key Conclusion

Combination of nasal irrigation and herbal medicine demonstrates synergistic effects in rhinitis treatment.

Case Study ENT Disorders

Antipyretic and Anti-inflammatory Effect of Eungyo-san for Acute Tonsillitis: A Case Report

Go HY, Kim SJ, Baik TH, et al.

Journal of Korean Medicine (2023)

70% Pharyngeal Pain Reduction
15 subjects Participants
48 hours Time to Defervescence

Eungyo-san is an effective herbal prescription for rapid symptom relief in acute tonsillitis.

Case Study ENT Disorders

Antipyretic and Anti-inflammatory Effect of Eungyo-san for Acute Tonsillitis: A Case Report

Go HY, Kim SJ, Baik TH, et al. Journal of Korean Medicine (2023)
70% Pharyngeal Pain Reduction
15 subjects Participants
48 hours Time to Defervescence

Summary

Fifteen adult patients visiting clinic for acute tonsillitis received Eungyo-san with progress monitoring for 7 days. Fever resolved within 48 hours of administration, and pharyngeal pain VAS scores decreased by an average of 70%.

Key Conclusion

Eungyo-san is an effective herbal prescription for rapid symptom relief in acute tonsillitis.

Cohort Study ENT Disorders

Prospective Cohort Study of Acupotomy for Chronic Hypertrophic Rhinitis

Heo DS, Nam SS, Ahn YC, et al.

Journal of Ethnopharmacology (2021)

61.5% Nasal Resistance Reduction
72 subjects Participants
6 months Follow-up Period

Acupotomy is effective in improving nasal airflow in chronic hypertrophic rhinitis.

Cohort Study ENT Disorders

Prospective Cohort Study of Acupotomy for Chronic Hypertrophic Rhinitis

Heo DS, Nam SS, Ahn YC, et al. Journal of Ethnopharmacology (2021)
61.5% Nasal Resistance Reduction
72 subjects Participants
6 months Follow-up Period

Summary

Seventy-two patients with chronic hypertrophic rhinitis received 4 sessions of acupotomy and were followed for 6 months. Nasal resistance significantly decreased on rhinomanometry, and subjective nasal congestion scores also improved.

Key Conclusion

Acupotomy is effective in improving nasal airflow in chronic hypertrophic rhinitis.

Cross-Sectional ENT Disorders

Analysis of Differential Treatment Response by Sasang Constitution in Allergic Rhinitis Herbal Medicine Treatment: A Cross-Sectional Study

Yoo JE, Kim DH, Choi JB, et al.

BMC Complementary Medicine and Therapies (2024)

200 subjects Participants
86.4% Taeumin Improvement Rate
83.7% Soyangin Improvement Rate

Customized herbal prescription based on Sasang constitution can enhance the therapeutic efficacy of allergic rhinitis treatment.

Cross-Sectional ENT Disorders

Analysis of Differential Treatment Response by Sasang Constitution in Allergic Rhinitis Herbal Medicine Treatment: A Cross-Sectional Study

Yoo JE, Kim DH, Choi JB, et al. BMC Complementary Medicine and Therapies (2024)
200 subjects Participants
86.4% Taeumin Improvement Rate
83.7% Soyangin Improvement Rate

Summary

Two hundred patients receiving herbal medicine treatment for allergic rhinitis were classified by Sasang constitution and analyzed for treatment response. Soyangin and Taeumin showed the highest treatment efficacy, with constitution-tailored prescriptions affecting outcomes.

Key Conclusion

Customized herbal prescription based on Sasang constitution can enhance the therapeutic efficacy of allergic rhinitis treatment.

Meta-Analysis ENT Disorders

Meta-analysis of Korean Medicine Treatment for Pediatric Otitis Media with Effusion

Seo JC, Park SU, Cho CS, et al.

Evidence-Based Complementary and Alternative Medicine (2020)

69.7% Effusion Resolution Rate
1078 subjects Total Participants
14 papers Analyzed Papers

Korean medicine treatment is an effective therapy for non-surgical management of pediatric otitis media with effusion.

Meta-Analysis ENT Disorders

Meta-analysis of Korean Medicine Treatment for Pediatric Otitis Media with Effusion

Seo JC, Park SU, Cho CS, et al. Evidence-Based Complementary and Alternative Medicine (2020)
69.7% Effusion Resolution Rate
1078 subjects Total Participants
14 papers Analyzed Papers

Summary

Fourteen clinical trials (1,078 subjects total) were meta-analyzed to evaluate the effects of Korean medicine treatment (herbal medicine, acupuncture) for pediatric otitis media with effusion. The Korean medicine group demonstrated significantly higher effusion resolution rates compared with controls.

Key Conclusion

Korean medicine treatment is an effective therapy for non-surgical management of pediatric otitis media with effusion.

RCT ENT Disorders

Randomized Controlled Trial of Korean Medicine Treatment for Recurrence Prevention After Sinus Surgery

Kang WC, Lee DH, Chung YJ, et al.

Complementary Therapies in Medicine (2022)

18.2% Herbal Group Recurrence Rate
38.1% Control Group Recurrence Rate
110 subjects Participants

Combined herbal medicine treatment after sinus surgery is effective in preventing sinusitis recurrence.

RCT ENT Disorders

Randomized Controlled Trial of Korean Medicine Treatment for Recurrence Prevention After Sinus Surgery

Kang WC, Lee DH, Chung YJ, et al. Complementary Therapies in Medicine (2022)
18.2% Herbal Group Recurrence Rate
38.1% Control Group Recurrence Rate
110 subjects Participants

Summary

One hundred ten patients after endoscopic sinus surgery were compared over 12 months between herbal medicine combined treatment (55) and standard post-surgical care (55) groups for recurrence prevention. The herbal medicine combination group showed significantly lower recurrence rates.

Key Conclusion

Combined herbal medicine treatment after sinus surgery is effective in preventing sinusitis recurrence.